Computational and Experimental Approaches in Multi-Target Pharmacology

Thomas J. Anastasio

systems biology; computer modeling; drug repurposing; synergy; drug discovery; drug combination; high throughput screening; multidrug therapeutics; polypharmacy; multifactorial process

The next frontier in pharmacology is the development of multi-target strategies in which pathological processes are controlled by pharmacologically manipulating them at many different points at once. Designing multi-target strategies will require deep understanding of the complex physiology that underlies pathological processes. It will also require the development of single drugs with multiple targets, or combinations of drugs with compatible pharmacokinetics that work synergistically to maximi

Frontiers Media SA

2017

PDF

9782889452521

https://directory.doabooks.org/handle/20.500.12854/43699

Eng

https://creativecommons.org/licenses/by/4.0/

Pharmacology