Future Challenges for the Diagnosis and Management of Affective Disorders_From Preclinical Evidence to Clinical Trials

Antonio Ventriglio, Mario Luciano and Andrea Fiorillo

perinatal depression; attachment style; coping strategies; gender medicine; structural equation modelling; family psychoeducation; major depression; caregiver; family burden; relapse rates; depressive symptoms; social contacts; brain-derived neurotrophic factor; BDNF; bipolar disorder; BDNF-TrkB signaling; inflammatory factors; suicidal ideation; Beck Scale; major depressive disorder; bipolar disorder; polarity at onset; affective temperaments; manic/hypomanic polarity; depressive polarity; psyc

This Special Issue presents preclinical and clinical research aimed at reframing the diagnosis and treatment of affective disorders beyond classical neurobiological models. It includes a meta-analysis comparing single- versus two-dose psilocybin administration in major depressive disorder, clarifying its efficacy and dose-dependency. Another study uses network analysis of exposome scores to link environmental exposure with multidimensional psychopathology in non-clinical samples, while the effec

journal Brain Sciences

2026

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pdf

978-3-7258-6072-2

https://doi.org/10.3390/books978-3-7258-6072-2

Eng

https://creativecommons.org/licenses/by-nc-nd/4.0/

Psychology